| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Prospero homeobox protein 1;Homeobox prospero-like protein PROX1;PROX-1;PROX1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human EPHX2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-EPHX2 Rabbit Monoclonal Antibody catalog # M01999-3. Tested in WB application. This antibody reacts with Human.
Protein: Lysosome-associated membrane glycoprotein 2 (Lamp2) | Gene: Prospero homeobox protein 1 | Target: EPHX2 | Function: Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. . | Research areas: Adapters,Apoptosis,Cancer,Cell Biology,Cell Cycle,Cell Differentiation,Cytoplasmic,Intracellular,Kinases,MAPK Pathway,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 29E21 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human EPHX2 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 70 kDa | Calculated MW: 83203 MW
Cellular localization: Nucleus . RORG promotes its nuclear localization. .
Tissue details: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas. .
Status: Active
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