| Field | Specification |
|---|---|
| Target | |
| Alternative names | Exosome complex component RRP42; Exosome component 7; Ribosomal RNA-processing protein 42; p8; EXOSC7; KIAA0116; RRP42 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from EXOSC7 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 26E67 is a rabbit monoclonal antibody that recognizes exosome complex component RRP42 (gene EXOSC7) in human samples and is validated for Western blot and ICC/IF. The predicted molecular weight is 31.8 kDa, and the supplier reports an observed band at about 32 kDa.
EXOSC7 (RRP42) is one of the six ring subunits forming the barrel-shaped core of the RNA exosome. The complex channels RNA to its associated nucleases for 3′-5′ degradation, supporting maturation of rRNA and small RNAs and turnover of unstable transcripts.
| Target | Exosome complex component RRP42 (gene EXOSC7; UniProt Q15024, human) |
|---|---|
| Clone | 26E67 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 31.8 kDa |
| Observed MW | 32 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Samples with a confirmed band (WB): HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of EXOSC7.
Reactivity Notes
The supplier lists reactivity with human. UniProt places exosome complex component RRP42 in the nucleus and cytoplasm. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
