| Field | Specification |
|---|---|
| Target | |
| Alternative names | Fibroblast growth factor 21;FGF-21;FGF21;UNQ3115/PRO10196; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human FGF21 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AG-6 is a rabbit monoclonal antibody that recognizes fibroblast growth factor 21 (gene FGF21) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 22.3 kDa, and the supplier reports an observed band at about 22 kDa.
Fibroblast growth factor 21 (FGF21) is an endocrine FGF made mainly by the liver in response to fasting and nutritional stress. It signals through FGF receptors together with the coreceptor β-Klotho to increase glucose uptake in fat cells and improve insulin sensitivity. FGF21 is widely studied in energy metabolism, obesity and metabolic disease.
| Target | Fibroblast growth factor 21 (gene FGF21; UniProt Q9NSA1, human) |
|---|---|
| Clone | AG-6 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 22.3 kDa |
| Observed MW | 22 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human FGF21.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes fibroblast growth factor 21 as a secreted protein.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
