| Field | Specification |
|---|---|
| Target | |
| Alternative names | Importin subunit alpha; Karyopherin subunit alpha; Pendulin; Pen |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects importin subunit alpha (gene Pen) in Fruit fly samples.
In Drosophila, pendulin (Pen) is an importin-α family nuclear import receptor. It recognizes classical nuclear localization signals on cargo proteins and, with importin-β, carries them to the nuclear pore. It is needed for normal cell division, and loss of pendulin affects hematopoietic cells in the fly, where it has been linked to blood cell overgrowth.
| Target | Importin subunit alpha (gene Pen; UniProt P52295, Drosophila) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Fruit fly |
| Form | Liquid |
| Formulation | 20 mM PBS; 50% glycerol; 0.02% NaN3 |
| Storage | Store at −20 °C for up to 12 months or 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Reactivity Notes
The supplier lists reactivity with Fruit fly. UniProt places importin subunit alpha in the cytoplasm and nucleus. Tissue expression noted by UniProt (Drosophila): Predominantly expressed in the neuroblast stem cells.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
