| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Transcription factor HES-1;Class B basic helix-loop-helix protein 39;bHLHb39;Hairy and enhancer of split 1;Hairy homolog;Hairy-like protein;hHL;HES1;BHLHB39, HL, HRY; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human GALT |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-GALT Rabbit Monoclonal Antibody catalog # M01460. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Protein: Glycogen synthase kinase-3 beta (gsk3b) | Gene: Transcription factor HES-1 | Target: GALT | Function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage. . | Research areas: Epigenetics and Nuclear Signaling,Neurogenesis,Neurology Process,Neuroscience,Transcription,Transcription Factors
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 29G81 | Isotype: IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthesized peptide derived from human GALT | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IF, ICC
Observed MW: 43 kDa | Calculated MW: 29541 MW
Cellular localization: Nucleus.
Tissue details: Found on monocytes, neutrophils and eosinophil platelets.
Status: Active
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