| Field | Specification |
|---|---|
| Target | |
| Alternative names | Glomulin; FK506-binding protein-associated protein; FAP; FKBP-associated protein; GLMN; FAP48; FAP68; VMGLOM |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human GLMN recombinant protein (Position: Q153-R574). Human GLMN shares 85.4% amino acid (aa) sequence identity with mouse GLMN. |
| Purification | |
| Reconstitution | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects glomulin (gene GLMN) in human, mouse and rat samples and is validated for Western blot, flow cytometry and ELISA.
Glomulin (GLMN) binds the RING protein RBX1 within cullin-RING E3 ubiquitin ligases and blocks its interaction with the E2 enzyme, restraining ligase activity. It also helps keep components such as FBXW7 and cullins stable. It is needed for normal blood vessel development, and GLMN mutations cause glomuvenous malformations.
| Target | Glomulin (gene GLMN; UniProt Q92990, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human GLMN fragment (Gln153–Arg574), expressed in E. coli. Sequence identity with the mouse ortholog: 85.4%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. Tissue expression noted by UniProt (human): Ubiquitous.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
