Anti-GluR2+GluR3 Rabbit Monoclonal Antibody

Overview

This product is an anti-GRIA2/3 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone 18G36; isotype IgG; reactivity: Human,Mouse,Rat. Reported application contexts include WB, IP (as provided in the source record). Boster Bio Anti-GluR2+GluR3 Rabbit Monoclonal Antibody catalog # M02905-2. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Key elements and design rationale

• Target: GRIA2/3 (RNA-binding protein Musashi homolog 2).
• Antibody format: Monoclonal; clone 18G36; isotype IgG.
• Host: Rabbit.
• Species reactivity: Human,Mouse,Rat (confirm in your model system with appropriate controls).

This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.

Biological background

GRIA2/3 (protein: T-cell surface glycoprotein CD3 zeta chain) is a commonly studied target in molecular and cellular biology. Functional context (as provided): RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). . Reported cellular localization context: Cytoplasm. Associated with polysomes. . Tissue expression notes (as provided): Ubiquitous; detected at low levels. .

Research relevance and current trends

• Research context keywords from the source record include: Amino Acids,Neuroscience,Neurotransmission,Neurotransmitter,Receptors / Channels.
• Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
• Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.

Common research applications

• Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
• Immunoprecipitation (IP): enrich target complexes for downstream immunoblot or interaction analyses.

Workflow ideas (metafield): Validate GRIA2/3 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect GRIA2/3 expression by Western blot in cell or tissue lysates, Enrich GRIA2/3 by immunoprecipitation from lysates for downstream analysis

Notes for experimental interpretation

• Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
• Apparent molecular weight may vary by sample type and processing (observed MW: 136 kDa; calculated MW: 35197 MW).
• Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.

Additional product details (from the source record)

• Molecular weight (observed): 136 kDa
• Cellular localization (provided): Cytoplasm. Associated with polysomes. .
• Tissue details (provided): Ubiquitous; detected at low levels. .

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.