| Field | Specification |
|---|---|
| Target | |
| Alternative names | Solute carrier family 2, facilitated glucose transporter member 3;Glucose transporter type 3, brain;GLUT-3;SLC2A3;GLUT3; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human GLUT3 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ABHB-19 is a rabbit monoclonal antibody that recognizes solute carrier family 2, facilitated glucose transporter member 3 (gene SLC2A3) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 53.9 kDa, and the supplier reports an observed band at about 54 kDa.
GLUT3 (SLC2A3) is a high-affinity facilitative glucose transporter often called the neuronal glucose transporter. It supplies glucose to neurons and is also expressed in sperm, placenta and some immune cells, and many tumors upregulate it to fuel growth.
| Target | Solute carrier family 2, facilitated glucose transporter member 3 (gene SLC2A3; UniProt P11169, human) |
|---|---|
| Clone | ABHB-19 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 53.9 kDa |
| Observed MW | 54 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): human HepG2 cells, human 293T cells, human A431 cells, human SH-SY5Y cells, rat kidney tissue, rat brain tissue, mouse kidney tissue, mouse brain tissue lysates.
Recommended loading (WB): 20–40 µg of total protein per lane.
Conditions in the example images (WB): 5–20% gradient SDS-PAGE under reducing conditions, 30 µg lysate per lane, transfer to nitrocellulose membrane, blocking in 5% non-fat milk, primary antibody at 1:500 overnight at 4 °C, HRP-conjugated secondary antibody at 1:500, ECL detection.
Samples with confirmed staining (IHC): human colon cancer tissue, human stomach cancer tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Synthetic peptide based on the sequence of human GLUT3.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places solute carrier family 2, facilitated glucose transporter member 3 in the cell membrane, perikaryon and cell projection. Tissue expression noted by UniProt (human): Highly expressed in brain. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Yi Ding et al. (2026) SLC2A3-Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion. Advanced Science. 10.1002/advs.202516622
Fan Chen et al. (2022) Construction of the experimental rat model of gestational diabetes. PLoS One. 10.1371/journal.pone.0273703
