| Field | Specification |
|---|---|
| Target | |
| Alternative names | Glutamate receptor ionotropic, kainate 2; GluK2; Excitatory amino acid receptor 4; EAA4; Glutamate receptor 6; GluR-6; GluR6; GRIK2 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human GRIK2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24G39 is a rabbit monoclonal antibody that recognizes glutamate receptor ionotropic, kainate 2 (gene GRIK2) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 102.6 kDa, and the supplier reports an observed band at about 103 kDa.
GluK2 (GRIK2) is a subunit of kainate-type ionotropic glutamate receptors widely expressed in the brain. It forms functional channels alone or with other kainate subunits and contributes to synaptic transmission and plasticity, with GRIK2 variants linked to neurodevelopmental disorders.
| Target | Glutamate receptor ionotropic, kainate 2 (gene GRIK2; UniProt Q13002, human) |
|---|---|
| Clone | 24G39 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 102.6 kDa |
| Observed MW | 103 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): A431 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human GRIK2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places glutamate receptor ionotropic, kainate 2 in the cell membrane and postsynaptic cell membrane. Tissue expression noted by UniProt (human): Expression is higher in cerebellum than in cerebral cortex. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
