| Field | Specification |
|---|---|
| Target | |
| Alternative names | HBZ; HBZ2; Hemoglobin subunit zeta; HBAZ; Hemoglobin zeta chain; Zeta-globin |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human HBZ recombinant protein (Position: D48-R142). Human HBZ shares 80% amino acid (aa) sequence identity with mouse HBZ. |
| Purification | |
| Reconstitution | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects hemoglobin subunit zeta (gene HBZ) in mouse and rat samples and is validated for Western blot and ELISA.
Hemoglobin subunit zeta (HBZ) is an alpha-type globin chain made in the yolk sac during early embryonic life. It combines with epsilon or gamma chains to form embryonic hemoglobins before being replaced by alpha globin. HBZ is studied in globin gene switching and developmental hematopoiesis.
| Target | Hemoglobin subunit zeta (gene HBZ; UniProt P02008, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human HBZ fragment (Asp48–Arg142), expressed in E. coli. Sequence identity with the mouse ortholog: 80%.
Reactivity Notes
The supplier lists reactivity with mouse and rat. Tissue expression noted by UniProt (human): Detected in fetal erythrocytes (at protein level).
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
