| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Glucocorticoid receptor;GR;Nuclear receptor subfamily 3 group C member 1;NR3C1;GRL; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human HFE |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-HFE Rabbit Monoclonal Antibody catalog # M00506. Tested in WB application. This antibody reacts with Human.
Protein: T-cell surface glycoprotein CD4 | Gene: Glucocorticoid receptor | Target: HFE | Function: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. . | Research areas: 2339,Domain Families,Epigenetics and Nuclear Signaling,Nuclear Hormone Receptors,Nuclear Receptors,Nuclear Signaling Pathways,Signal Transduction,Signaling Pathway,Transcription,Zinc Finger
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 27H20 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human HFE | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 40 kDa | Calculated MW: 85659 MW
Cellular localization: Cytoplasm . Mitochondrion. Nucleus . Cytoplasmic in the absence of ligand, nuclear after ligand- binding.
Tissue details: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. .
Status: Active
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