| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Adiponectin receptor protein 1;Progestin and adipoQ receptor family member I;ADIPOR1;PAQR1 , TESBP1A;CGI-45; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human HMGCL |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-HMGCL Rabbit Monoclonal Antibody catalog # M01886. Tested in WB, IHC applications. This antibody reacts with Human.
Protein: Lysosome-associated membrane glycoprotein 2 (Lamp2) | Gene: Adiponectin receptor protein 1 | Target: HMGCL | Function: Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity). . | Research areas: Cancer,Cancer Metabolism,Endocrine Metabolism,Growth Factors/Hormones,Hormone Biosynthesis,Metabolic Signaling Pathway,Metabolism,Pathways and Processes,Signal Transduction
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30H50 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human HMGCL | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC
Observed MW: 30 kDa | Calculated MW: 42616 MW
Cellular localization: Cell membrane ; Multi-pass membrane protein . Localized to the cell membrane and intracellular organelles. .
Tissue details: Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Weakly expressed in colon, thymus and small intestine (PubMed:12802337). .
Status: Active
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