| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | AICD-57, A4, Beta-CTF, Protease nexin-II, Gamma-CTF(50), ABPP, S-APP-beta, APP, Abeta40, Abeta42, AID(59), Amyloid intracellular domain 59, AID(57), S-APP-alpha, Gamma-CTF(59), Beta-secretase C-terminal fragment, Amyloid-beta precursor protein, Amyloid precursor protein, Beta-APP42, PreA4, Alzheimer disease amyloid protein, APPI, PN-II, AICD-59, Alpha-secretase C-terminal fragment, Amyloid-beta A4 protein, Amyloid intracellular domain 57, CVAP, Amyloid intracellular domain 50, Beta-APP40, AD1, Cerebral vascular amyloid peptide, AID(50), Alpha-CTF, Gamma-CTF(57), AICD-50 |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
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| Target |
Overview
Anti-Human APP Nanobody (SAA1209) targets APP (Alzheimer disease amyloid protein). Frequently used across ELISA, IHC, WB workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Neuroscience research.
Also known as: Alzheimer disease amyloid protein, Amyloid-beta precursor protein, Cerebral vascular amyloid peptide, Amyloid intracellular domain 59, Amyloid precursor protein, Amyloid intracellular domain 57, Amyloid intracellular domain 50, Alpha-secretase C-terminal fragment.
Target biology
APP (Alzheimer disease amyloid protein) is annotated as alzheimer disease amyloid protein and is commonly profiled for expression and localization in relevant model systems. It is frequently investigated in contexts related to Neuroscience. Common alternative names and symbols used in the literature include: Amyloid-beta precursor protein, Cerebral vascular amyloid peptide, Amyloid intracellular domain 59, Amyloid precursor protein, Amyloid intracellular domain 57, Amyloid intracellular domain 50, Alpha-secretase C-terminal fragment. Based on the annotated name/class, the target is most often associated with context-dependent localization, though this can vary by model system.
How this antibody helps
As a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
- For Western blotting, use fresh protease (and phosphatase, if relevant) inhibitors and confirm the primary band at the expected molecular weight; additional bands may reflect isoforms or processing.
- For IHC, optimize fixation and antigen retrieval (buffer/pH/heat) and include an isotype/secondary-only control to assess background.
- For ELISA, optimize capture/detection pairing and run a standard curve in matrix-matched diluent when possible.
Additional notes
For research use only.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
