| Field | Specification |
|---|---|
| Target | |
| Alternative names | G1/S-specific cyclin-E1; CCNE1; CCNE |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
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| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets G1/S-specific cyclin-E1 (gene CCNE1) in human samples and is validated for ICC/IF. The predicted molecular weight is 47.1 kDa.
Cyclin E1 (CCNE1) activates CDK2 in late G1 to promote the transition into S phase and the start of DNA replication. It is tightly regulated by ubiquitin-mediated degradation, and CCNE1 amplification is well documented in several cancers, notably high-grade serous ovarian cancer.
| Target | G1/S-specific cyclin-E1 (gene CCNE1; UniProt P24864, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | 20 mM PBS; 50% glycerol; 0.02% NaN3 |
| Calculated MW | 47.1 kDa |
| Storage | Store at −20 °C for up to 12 months or 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Immunocytochemistry / Immunofluorescence | Not specified by the supplier |
|---|
Reactivity Notes
The supplier lists reactivity with human. UniProt places G1/S-specific cyclin-E1 in the nucleus. Tissue expression noted by UniProt (human): Highly expressed in testis and placenta.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
