| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | MSK21, MAC-inhibitory protein, MEM43 antigen, MAC-IP, MIN2, MIRL, HRF20, Protectin, 1F5 antigen, MIC11, MIN3, Membrane inhibitor of reactive lysis, MACIF, 20 kDa homologous restriction factor, CD59, MIN1, CD59 glycoprotein, HRF-20, Membrane attack complex inhibition factor |
| Clonality | |
| Concentration | |
| Conjugate | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Overview
Anti-Human CD59 Antibody (TS59), APC targets CD59 (Membrane attack complex inhibition factor). Frequently used across FCM workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Immunology & Inflammation research.
Also known as: Membrane attack complex inhibition factor, 20 kDa homologous restriction factor, Membrane inhibitor of reactive lysis, MAC-inhibitory protein, CD59 glycoprotein, MEM43 antigen, 1F5 antigen, MAC-IP, HRF-20, Protectin.
Target biology
CD59 (Membrane attack complex inhibition factor) is a pathogen-derived antigen commonly used to detect infection, antigen expression, or immune responses in research assays. Envelope/glycoprotein antigens are often surface-exposed and may be assessed for expression, trafficking, and antibody recognition in cell-based systems. Assay performance can depend on native conformation, glycosylation, and sample preparation conditions. Common alternative names and symbols used in the literature include: 20 kDa homologous restriction factor, Membrane inhibitor of reactive lysis, MAC-inhibitory protein, CD59 glycoprotein, MEM43 antigen, 1F5 antigen, MAC-IP, HRF-20, Protectin, MSK21. Based on the annotated name/class, the target is most often associated with plasma membrane and/or intracellular membranes localization, though this can vary by model system.
How this antibody helps
As a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.