| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Fetal Alzheimer antigen, FALZ, Nucleosome-remodeling factor subunit BPTF, FAC1, BPTF, Fetal Alz-50 clone 1 protein, Bromodomain and PHD finger-containing transcription factor |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target |
Overview
Antibody against FALZ/BPTF IP (Bromodomain and PHD finger-containing transcription factor) for research detection of protein expression and localization.
Target biology
FALZ is a transcription factor or transcriptional regulator that modulates gene-expression programs in response to developmental or environmental cues. These proteins often act downstream of signaling pathways and are assessed for expression level, subcellular localization and pathway activation states.
Expected localization
Primarily nuclear when active; many are regulated by cytoplasmic sequestration and stimulus-dependent nuclear import.
Research context
This target is frequently studied in the context of Molecular & Cellular Biology research. Application suitability (e.g., ELISA, IF, IP) is indicated in the specifications; conditions should be optimized by titration. Species reactivity information is provided in the specifications (reported: Human, Mouse).
Recommended experimental notes
- For IF/ICC, adjust permeabilization (e.g., mild detergent vs stronger conditions) based on expected localization; include secondary-only and isotype controls for background.
- For IP, use gentle lysis to preserve complexes and include an IgG control; validate enrichment by immunoblot or orthogonal detection.
- For ELISA, ensure capture/detection antibody compatibility and run a standard curve; verify sample matrix effects with spike-and-recovery and dilution linearity.
Controls & interpretation
Where possible, confirm specificity using genetic perturbation (KO/KD/CRISPR), peptide competition (if applicable), or an orthogonal readout. Include a negative control sample expected to express low/none of FALZ/BPTF IP, and a positive control sample known to express FALZ/BPTF IP.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.