| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Ig gamma-1 chain C region;IGHG1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human IgG1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-Human IgG1 Rabbit Monoclonal Antibody catalog # M04575-6. Tested in WB application. This antibody reacts with Human.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Ig gamma-1 chain C region | Target: IGHG1 | Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. . | Research areas: Immunoglobulins,Immunology
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 27I03 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human IgG1 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB
Observed MW: 52 kDa | Calculated MW: 36106 MW
Cellular localization: Secreted.
Tissue details: According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.
Status: Active
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