| Field | Specification |
|---|---|
| Target | |
| Alternative names | Small kinetochore-associated protein; SKAP; Kinetochore-localized astrin-binding protein; Kinastrin; Kinetochore-localized astrin/SPAG5-binding protein; TRAF4-associated factor 1; KNSTRN; C15orf23; TRAF4AF1 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets small kinetochore-associated protein (gene KNSTRN) in human samples. The predicted molecular weight is 35.4 kDa.
Kinastrin (KNSTRN, also called SKAP) is a small kinetochore protein that works with astrin (SPAG5) at kinetochores and spindle microtubules. The astrin–kinastrin complex stabilizes kinetochore–microtubule attachments, supporting chromosome alignment, timely anaphase onset and spindle pole integrity. KNSTRN mutations have been reported in cutaneous squamous cell carcinoma.
| Target | Small kinetochore-associated protein (gene KNSTRN; UniProt Q9Y448, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | 20 mM PBS; 50% glycerol; 0.02% NaN3 |
| Calculated MW | 35.4 kDa |
| Storage | Store at −20 °C for up to 12 months or 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Reactivity Notes
The supplier lists reactivity with human. UniProt places small kinetochore-associated protein in the nucleus, chromosome and cytoplasm. Tissue expression noted by UniProt (human): Widely expressed, including in skin.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
