| Field | Specification |
|---|---|
| Target | |
| Alternative names | Histone-arginine methyltransferase METTL23; Methyltransferase-like protein 23; METTL23; C17orf95 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
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| Conjugate | |
| Molecular weight | |
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| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
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Product Overview
This rabbit polyclonal antibody targets histone-arginine methyltransferase METTL23 in human and mouse samples. The predicted molecular weight is 21.5 kDa.
METTL23 is a methyltransferase that produces asymmetric dimethylation of histone H3 at arginine 17 (H3R17me2a). In the early mouse embryo, it acts as a maternal factor that helps reprogram the paternal genome, supporting DNA demethylation in the male pronucleus. Mutations in METTL23 are associated with intellectual disability, and it is studied in chromatin regulation.
| Target | Histone-arginine methyltransferase METTL23 (gene METTL23; UniProt Q86XA0, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse |
| Form | Liquid |
| Formulation | 20 mM PBS; 50% glycerol; 0.02% NaN3 |
| Calculated MW | 21.5 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
Samples with a confirmed band (WB): human HCT cells, human Caco-2 cells, human SHY cells, human U87 cells, mouse GL261 cells.
Reactivity Notes
The supplier lists reactivity with human and mouse. UniProt places histone-arginine methyltransferase METTL23 in the nucleus and cytoplasm.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
