| Field | Specification |
|---|---|
| Alternative Names | PTPRN; ICA3; ICA512; Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; Islet cell antigen 512; ICA 512; Islet cell autoantigen 3; PTP IA-2 [Cleaved into: ICA512-N-terminal fragment; ICA512-NTF; ICA512-transmembrane fragment; ICA512-TMF; ICA512-cleaved cytosolic fragment; ICA512-CCF] |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human IA-2/PTPRN recombinant protein (Position: V35-H569). Human IA-2/PTPRN shares 79.5% amino acid (aa) sequence identity with rat IA-2/PTPRN. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-IA-2/PTPRN Antibody Picoband® catalog # A03116-1. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Cross reactivity: No cross-reactivity with other proteins
Protein: Receptor-type tyrosine-protein phosphatase-like N | Gene: protein tyrosine phosphatase receptor type N | Target: PTPRN
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: E.coli-derived human IA-2/PTPRN recombinant protein (Position: V35-H569). Human IA-2/PTPRN shares 79.5% amino acid (aa) sequence identity with rat IA-2/PTPRN. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, ELISA
Observed MW: 106 kDa | Calculated MW: 106 kDa
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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