| Field | Specification |
|---|---|
| Target | |
| Alternative names | Interferon alpha/beta receptor 1;IFN-R-1;IFN-alpha/beta receptor 1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;CRF2-1;Type I interferon receptor 1;IFNAR1;IFNAR; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human IFNAR1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone DDC-9 is a rabbit monoclonal antibody that recognizes interferon alpha/beta receptor 1 (gene IFNAR1) in human samples and is validated for Western blot, immunoprecipitation and flow cytometry. The predicted molecular weight is 63.5 kDa; the supplier reports observed bands at 90, 130 kDa.
IFNAR1 is one of the two chains of the type I interferon receptor, which responds to interferons alpha, beta, omega and related cytokines. Interferon binding brings IFNAR1 and IFNAR2 together and activates the associated kinases TYK2 and JAK1, leading to STAT phosphorylation and expression of interferon-stimulated genes.
| Target | Interferon alpha/beta receptor 1 (gene IFNAR1; UniProt P17181, human) |
|---|---|
| Clone | DDC-9 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 63.5 kDa |
| Observed MW | 90, 130 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunoprecipitation | 1:20 |
| Flow cytometry | 1:20 |
Immunogen
Synthetic peptide based on the sequence of human IFNAR1.
Reactivity Notes
The supplier lists reactivity with human. Tissue expression noted by UniProt (human): IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
