| Field | Specification |
|---|---|
| Target | |
| Alternative names | Interferon gamma receptor 1; IFN-gamma receptor 1; IFN-gamma-R1; Interferon gamma receptor alpha-chain; IFN-gamma-R-alpha; CD antigen CD119; Ifngr1; Ifngr |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derivedmouseIfngr1recombinantprotein(Position:L45-Q347).MouseIfngr1shares?54.2%?amino?acid?(aa)?sequence?identity?withhumanIFNGR1. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects interferon gamma receptor 1 (gene Ifngr1) in mouse and rat samples and is validated for Western blot and ELISA. The predicted molecular weight is 52.3 kDa, and the supplier reports an observed band at about 96 kDa.
IFNGR1 is the ligand-binding chain of the interferon-γ receptor, which pairs with IFNGR2 to form the functional receptor. Interferon-γ binding activates JAK1 and JAK2, leading to STAT1 phosphorylation and expression of genes that boost macrophage activation, antigen presentation and defense against intracellular pathogens.
| Target | Interferon gamma receptor 1 (gene Ifngr1; UniProt P15261, mouse) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Mouse, Rat |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Calculated MW | 52.3 kDa |
| Observed MW | 96 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Samples with a confirmed band (WB): rat thymus tissue, mouse thymus tissue, mouse spleen tissue, mouse lung tissue, mouse RAW264.7 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
E. coli-derivedmouseIfngr1recombinantprotein(Position:L45-Q347).MouseIfngr1shares?54.2%?amino?acid?(aa)?sequence?identity?withhumanIFNGR1.
Reactivity Notes
The supplier lists reactivity with mouse and rat. UniProt places interferon gamma receptor 1 in the cell membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
