| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Insulin-like growth factor I;IGF-I;Mechano growth factor;MGF;Somatomedin-C;IGF1;IBP1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human IGF1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-IGF1/Igf I Rabbit Monoclonal Antibody is an antibody targeting IGF1. Common applications include WB. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: DBG-9; isotype: Rabbit IgG; reactivity: Recombinant protein; observed MW: 95 kDa; calculated MW: 21841 MW.
Boster Bio Anti-IGF1/Igf I Rabbit Monoclonal Antibody catalog # M00148. Tested in WB application. This antibody reacts with recombinant protein.
Key elements and design rationale
- Target: IGF1 — Insulin-like growth factor I
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: DBG-9; Isotype: Rabbit IgG
- Species reactivity: Recombinant protein
- Molecular weight guidance: Observed: 95 kDa; Calculated: 21841 MW
Biological background
Protein function (datasheet): The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. .
Cellular localization (datasheet): Secreted.
Tissue details (datasheet): Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Developmental Biology,Growth Factors,Growth Factors/Hormones,Signal Transduction.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
