| Field | Specification |
|---|---|
| Alternative Names | Interleukin-1 beta;IL-1 beta;Catabolin;IL1B;IL1F2; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human IL-1 beta |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-IL-1 beta Rabbit Monoclonal Antibody catalog # M00101-3. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Mouse, Rat.
Protein: P2X purinoceptor 1 | Gene: Interleukin-1 beta | Target: Il1b | Function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. . | Research areas: Atherosclerosis,Cardiovascular,Cytokines,Immunology,Innate Immunity,Interleukins,Metabolism,Obesity,Vascular Inflammation
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 28I10 | Isotype: IgG | Reactivity: Mouse,Rat | Immunogen: A synthesized peptide derived from human IL-1 beta | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, ICC, FC, IP
Observed MW: 31 kDa, 28 kDa, 17 kDa | Calculated MW: 30748 MW
Cellular localization: Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Tissue details: Detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. .
Status: Active
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