| Field | Specification |
|---|---|
| Target | |
| Alternative names | Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; NKSF2; IL12B |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human IL12 p40 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24I67 is a rabbit monoclonal antibody that recognizes interleukin-12 subunit beta (gene IL12B) in human samples and is validated for Western blot. The predicted molecular weight is 37.2 kDa, and the supplier reports an observed band at about 40 kDa.
IL12B encodes the p40 subunit shared by interleukin-12 (with p35) and interleukin-23 (with p19). IL-12 promotes Th1 responses and IFN-γ production, while IL-23 supports Th17 responses, which makes p40 central to studies of cellular immunity and inflammatory disease.
| Target | Interleukin-12 subunit beta (gene IL12B; UniProt P29460, human) |
|---|---|
| Clone | 24I67 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 37.2 kDa |
| Observed MW | 40 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human IL12 p40.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes interleukin-12 subunit beta as a secreted protein.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
