| Field | Specification |
|---|---|
| Target | |
| Alternative names | Interleukin-15;IL-15;IL15; |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human IL-15 recombinant protein (Position: N49-S162). Human IL-15 shares 70% amino acid (aa) sequence identity with both mouse and rat IL-15. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects interleukin-15 (gene IL15) in human samples and is validated for ELISA and Western blot. The predicted molecular weight is 18.1 kDa, and the supplier reports an observed band at about 15 kDa.
Interleukin-15 (IL-15) is a cytokine that signals through the shared IL-2/IL-15Rβ and common γ chains, often presented in trans by IL-15Rα on neighboring cells. It is essential for the development and survival of NK cells and memory CD8+ T cells, so it is widely studied in antiviral and anti-tumor immunity.
| Target | Interleukin-15 (gene IL15; UniProt P40933, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3; plus stabilizers |
| Calculated MW | 18.1 kDa |
| Observed MW | 15 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| ELISA | 0.1–0.5 µg/mL |
|---|---|
| Western blot | 0.1–0.5 µg/mL (Human) |
Immunogen
Recombinant human IL-15 fragment (Asn49–Ser162), expressed in E. coli. Sequence identity with the mouse and rat orthologs: 70%.
Reactivity Notes
The supplier lists reactivity with human. Tissue expression noted by UniProt (human): Most abundant in placenta and skeletal muscle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xu Huan et al. (2021) Development of IL-15/IL-15Rα sushi domain-IgG4 Fc complexes in Pichia pastoris with potent activities and prolonged half-lives. Microbial Cell Factories. 10.1186/s12934-021-01605-3