| Field | Specification |
|---|---|
| Target | |
| Alternative names | Insulin receptor-related protein; IRR; IR-related receptor; INSRR |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Insulin Receptor R |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ADOI-9 is a rabbit monoclonal antibody that recognizes insulin receptor-related protein (gene INSRR) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 143.7 kDa, and the supplier reports an observed band at about 80 kDa.
The insulin receptor-related receptor (INSRR, also IRR) is a receptor tyrosine kinase related to the insulin and IGF-1 receptors. Rather than binding insulin, it acts as a sensor of alkaline extracellular pH, activating signaling through IRS1 and AKT, and it is expressed mainly in the kidney.
| Target | Insulin receptor-related protein (gene INSRR; UniProt P14616, human) |
|---|---|
| Clone | ADOI-9 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 143.7 kDa |
| Observed MW | 80 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human insulin Receptor R.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places insulin receptor-related protein in the membrane. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
