| Field | Specification |
|---|---|
| Target | |
| Alternative names | Integrin alpha-V;Vitronectin receptor subunit alpha;CD51;Integrin alpha-V heavy chain;Integrin alpha-V light chain;ITGAV;MSK8, VNRA; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Integrin alpha V |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone CCE-9 is a rabbit monoclonal antibody that recognizes integrin alpha-V (gene ITGAV) in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF and flow cytometry. The predicted molecular weight is 116.0 kDa; the supplier reports observed bands at 26, 125 kDa.
Integrin alpha-V (ITGAV, CD51) pairs with several beta subunits (β1, β3, β5, β6, β8) to form receptors that recognize the RGD motif in vitronectin, fibronectin, osteopontin and other matrix proteins. Alpha-V integrins also activate latent TGF-β, and they are studied in angiogenesis, fibrosis and tumor biology.
| Target | Integrin alpha-V (gene ITGAV; UniProt P06756, human) |
|---|---|
| Clone | CCE-9 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 116.0 kDa |
| Observed MW | 26, 125 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:1000–1:2000 |
|---|---|
| Immunohistochemistry | 1:100–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Flow cytometry | 1:20–1:100 |
Immunogen
Synthetic peptide based on the sequence of human integrin alpha V.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places integrin alpha-V in the cell membrane and cell junction.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
