| Field | Specification |
|---|---|
| Alternative Names | Interleukin-1 receptor-associated kinase 3;IRAK-3;2.7.11.1;IL-1 receptor-associated kinase M;IRAK-M;IRAK3 ; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human IRAK3 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-IRAK3/Irak M Rabbit Monoclonal Antibody is an antibody targeting IRAK3. Common applications include WB, IP. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: FDG-9; isotype: Rabbit IgG; reactivity: Human; observed MW: 130 kDa; calculated MW: 67767 MW.
Boster Bio Anti-IRAK3/Irak M Rabbit Monoclonal Antibody catalog # M02469. Tested in WB, IP applications. This antibody reacts with Human.
Key elements and design rationale
- Target: IRAK3 — Interleukin-1 receptor-associated kinase 3
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: FDG-9; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 130 kDa; Calculated: 67767 MW
Biological background
Protein function (datasheet): Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. .
Cellular localization (datasheet): Membrane; Single-pass type I membrane protein. Membrane, coated pit.
Tissue details (datasheet): Expressed predominantly in peripheral blood lymphocytes. .
Research relevance and current trends
- Commonly studied in contexts related to Innate Immunity,Interleukins,Protein Phosphorylation,Ser/Thr Kinases,Signal Transduction,TLR Signaling.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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