| Field | Specification |
|---|---|
| Target | |
| Alternative names | Interferon regulatory factor 6;IRF-6;IRF6; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human IRF6 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone GHD-9 is a rabbit monoclonal antibody that recognizes interferon regulatory factor 6 (gene IRF6) in human, mouse and rat samples and is validated for Western blot, IHC and ICC/IF. The predicted molecular weight is 53.1 kDa, and the supplier reports an observed band at about 53 kDa.
Interferon regulatory factor 6 (IRF6) is a transcription factor that controls the switch between proliferation and differentiation in keratinocytes. It is essential for normal skin and palate development, and mutations in IRF6 cause Van der Woude syndrome and popliteal pterygium syndrome.
| Target | Interferon regulatory factor 6 (gene IRF6; UniProt O14896, human) |
|---|---|
| Clone | GHD-9 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 53.1 kDa |
| Observed MW | 53 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Samples with a confirmed band (WB): Jurkat cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human IRF6.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places interferon regulatory factor 6 in the nucleus and cytoplasm. Tissue expression noted by UniProt (human): Expressed in normal mammary epithelial cells. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xin Zhou et al. (2018) Intact anti-LPS IgY is found in the blood after intragastric administration in mice. FEBS Open Bio. 10.1002/2211-5463.12571
