| Field | Specification |
|---|---|
| Target | |
| Alternative names | Histone acetyltransferase KAT7; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2; KAT7; HBO1; HBOa; MYST2 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human KAT7 / HBO1 / MYST2. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone ADAE-11 is a rabbit monoclonal antibody that recognizes histone acetyltransferase KAT7 in human, mouse and rat samples and is validated for Western blot, IHC, ICC/IF and immunoprecipitation. The predicted molecular weight is 70.6 kDa, and the supplier reports an observed band at about 75 kDa.
KAT7 (HBO1, MYST2) is a MYST family histone acetyltransferase and the catalytic subunit of HBO1 complexes. Depending on its scaffold partners, it acetylates histone H3 at Lys14 or histone H4 at Lys5, Lys8 and Lys12, supporting DNA replication licensing and transcription. It has roles in hematopoiesis, stem cell self-renewal and embryonic development and is studied in leukemia research.
| Target | Histone acetyltransferase KAT7 (gene KAT7; UniProt O95251, human) |
|---|---|
| Clone | ADAE-11 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 70.6 kDa |
| Observed MW | 75 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Immunoprecipitation | 1:20 |
Samples with a confirmed band (WB): MCF-7 cells, NIH/3T3 cells, C6 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human KAT7 / HBO1 / MYST2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places histone acetyltransferase KAT7 in the nucleus, chromosome and cytoplasm. Tissue expression noted by UniProt (human): Ubiquitously expressed, with highest levels in testis. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
