| Field | Specification |
|---|---|
| Alternative Names | Lysosome-associated membrane glycoprotein 1;LAMP-1;Lysosome-associated membrane protein 1;CD107 antigen-like family member A;CD107a;LAMP1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human LAMP1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-LAMP1/Cd107A Rabbit Monoclonal Antibody is an antibody targeting LAMP1. Common applications include WB, IHC. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: IIB-12; isotype: Rabbit IgG; reactivity: Human; observed MW: 15 kDa; calculated MW: 44882 MW.
Boster Bio Anti-LAMP1/Cd107A Rabbit Monoclonal Antibody catalog # M00780. Tested in WB, IHC applications. This antibody reacts with Human.
Key elements and design rationale
- Target: LAMP1 — Lysosome-associated membrane glycoprotein 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: IIB-12; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 15 kDa; Calculated: 44882 MW
Biological background
Protein function (datasheet): Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Cellular localization (datasheet): Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome. This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome.
Tissue details (datasheet): Isoform 1 is widely expressed, other isoforms are generally coexpressed with a more restricted distribution. Isoform 2 is expressed in skin, liver, skeletal muscle, cardiac muscle, placenta, umbilical vein endothelial cells, neuroblastoma cells, lymphoma cells, hepatoma cells and astrocytoma cells. Isoform 3 and isoform 4 are expressed in muscle, kidney, liver, placenta, cervical epithelium, umbilical vein endothelial cells, fibroblast cells, embryonal kidney cells, platelets and several blood cell lines. Isoform 4, rather than isoform 3, is selectively expressed in peripheral T-cells. Isoform 3 is expressed in non- proliferating and differentiated prostate gland epithelial cells and in platelets, on the surface of erythroleukemia cells and in various hematopoietic cell lines. Isoform 5 is expressed specifically in striated muscle (skeletal and cardiac muscle). .
Research relevance and current trends
- Commonly studied in contexts related to Cancer,Cell Death,Cell Type Marker,Hematopoietic Progenitors,Lymphoid,Metabolism,Metabolism Processes,Myeloid,Neurogenesis,Neurology Process,Neuron Marker,Neuroscience,Organelle Proteins,Organelles,Pathways and Processes,Protein Trafficking,Signal Transduction,Stem Cells,Subcellular Markers,T Lymphocytic Lineage,Tags & Cell Markers.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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