| Field | Specification |
|---|---|
| Target | |
| Alternative names | Platelet-activating factor acetylhydrolase IB subunit beta; Lissencephaly-1 protein; LIS-1; PAF acetylhydrolase 45 kDa subunit; PAF-AH 45 kDa subunit; PAF-AH alpha; PAFAH alpha; PAFAH1B1; LIS1; MDCR; MDS; PAFAHA |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human LIS1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 19P48 is a rabbit monoclonal antibody that recognizes platelet-activating factor acetylhydrolase IB subunit beta (gene PAFAH1B1) in human, mouse and rat samples and is validated for Western blot. The predicted molecular weight is 46.6 kDa, and the supplier reports an observed band at about 47 kDa.
LIS1 (PAFAH1B1) is a WD-repeat protein that regulates the microtubule motor dynein and is also the regulatory subunit of the enzyme PAF acetylhydrolase IB. It is required for nuclear movement and neuronal migration in the developing cortex, and mutations in the gene cause lissencephaly.
| Target | Platelet-activating factor acetylhydrolase IB subunit beta (gene PAFAH1B1; UniProt P43034, human) |
|---|---|
| Clone | 19P48 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 46.6 kDa |
| Observed MW | 47 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Immunogen
Synthetic peptide based on the sequence of human LIS1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places platelet-activating factor acetylhydrolase IB subunit beta in the cytoplasm and nuclear membrane. Tissue expression noted by UniProt (human): Fairly ubiquitous expression in both the frontal and occipital areas of the brain.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
