| Field | Specification |
|---|---|
| Target | |
| Alternative names | LLGL scribble cell polarity complex component 2; HGL; Lethal(2) giant larvae protein homolog 2; LLGL2 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human LLGL2 recombinant protein (Position: L102-Q553). Human LLGL2 shares 91.2% amino acid (aa) sequence identity with mouse LLGL2. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects LLGL scribble cell polarity complex component 2 (gene LLGL2) in human samples and is validated for Western blot, flow cytometry and ELISA.
LLGL2 is a mammalian homolog of the Drosophila lethal giant larvae tumor suppressor and a member of the Scribble polarity module. It interacts with the PAR6–aPKC complex and helps establish apical–basal polarity in epithelial cells, and it has been linked to spindle orientation during cell division. LLGL2 is studied in epithelial polarity and tissue organization.
| Target | LLGL scribble cell polarity complex component 2 (gene LLGL2; UniProt Q6P1M3, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|---|
| Flow cytometry (fixed cells) | 1–3 µg/1×106 cells (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human LLGL2 fragment (Leu102–Gln553), expressed in E. coli. Sequence identity with the mouse ortholog: 91.2%.
Reactivity Notes
The supplier lists reactivity with human. UniProt places LLGL scribble cell polarity complex component 2 in the cytoplasm.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
