| Field | Specification |
|---|---|
| Target | |
| Alternative names | Leucine-rich alpha-2-glycoprotein; LRG; LRG1 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human LRG1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 18L69 is a rabbit monoclonal antibody that recognizes leucine-rich alpha-2-glycoprotein (gene LRG1) in human samples and is validated for Western blot, IHC and immunoprecipitation. The predicted molecular weight is 38.2 kDa, and the supplier reports an observed band at about 45 kDa.
Leucine-rich alpha-2-glycoprotein (LRG1) is a secreted glycoprotein built from leucine-rich repeats and is present in human plasma. It has been reported to modulate TGF-β signaling in endothelial cells and to promote new blood vessel growth, and its circulating levels are widely measured in research on inflammation and vascular biology.
| Target | Leucine-rich alpha-2-glycoprotein (gene LRG1; UniProt P02750, human) |
|---|---|
| Clone | 18L69 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 38.2 kDa |
| Observed MW | 45 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunoprecipitation | 1:50 |
Samples with a confirmed band (WB): human plasma.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human LRG1.
Reactivity Notes
The supplier lists reactivity with human. UniProt describes leucine-rich alpha-2-glycoprotein as a secreted protein. Tissue expression noted by UniProt (human): Plasma. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
