| Field | Specification |
|---|---|
| Target | |
| Alternative names | Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; LRIG1; LIG1 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human LRIG1 recombinant protein (Position: K79-E906). Human LRIG1 shares 89.8% |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes leucine-rich repeats and immunoglobulin-like domains protein 1 (gene LRIG1) in human samples and is validated for Western blot and ELISA.
LRIG1 is a transmembrane protein with leucine-rich repeats and immunoglobulin-like domains that acts as a negative feedback regulator of receptor tyrosine kinases such as EGFR. By boosting receptor ubiquitination and speeding their breakdown inside the cell, it limits growth factor signaling, and it is studied in stem cell quiescence, epithelial homeostasis and tumor growth.
| Target | Leucine-rich repeats and immunoglobulin-like domains protein 1 (gene LRIG1; UniProt Q96JA1, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human LRIG1 fragment (Lys79–Glu906), expressed in E. coli.
Reactivity Notes
The supplier lists reactivity with human. UniProt places leucine-rich repeats and immunoglobulin-like domains protein 1 in the cell membrane. Tissue expression noted by UniProt (human): Widely expressed.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
