| Field | Specification |
|---|---|
| Target | |
| Alternative names | U7 snRNA-associated Sm-like protein LSm11; LSM11 |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human LSM11 recombinant protein (Position: A17-Q360). Human LSM11 shares 88.4% amino acid (aa) sequence identity with mouse LSM11. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets U7 snRNA-associated Sm-like protein LSm11 in human and rat samples and is validated for Western blot and ELISA.
LSM11 is an Sm-like protein that belongs to the U7 snRNP, the small nuclear ribonucleoprotein that processes the 3′ ends of replication-dependent histone pre-mRNAs. It binds the special Sm-binding site of U7 snRNA, and because histone mRNA processing is tied to DNA replication, it is studied in cell-cycle progression from G1 to S phase.
| Target | U7 snRNA-associated Sm-like protein LSm11 (gene LSM11; UniProt P83369, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human LSM11 fragment (Ala17–Gln360), expressed in E. coli. Sequence identity with the mouse ortholog: 88.4%.
Reactivity Notes
The supplier lists reactivity with human and rat. UniProt places U7 snRNA-associated Sm-like protein LSm11 in the nucleus.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
