| Field | Specification |
|---|---|
| Target | |
| Alternative names | Mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; Paracaspase; MALT1; MLT |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human MALT1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 23M89 is a rabbit monoclonal antibody that recognizes mucosa-associated lymphoid tissue lymphoma translocation protein 1 (gene MALT1) in human samples and is validated for Western blot and ICC/IF. The predicted molecular weight is 92.3 kDa, and the supplier reports an observed band at about 92 kDa.
MALT1 is a paracaspase that, together with CARD11 (or CARD9/CARD14) and BCL10, forms the CBM signaling complex downstream of antigen and pattern-recognition receptors. It acts both as a scaffold that recruits TRAF6 to activate NF-κB and as a protease that cleaves negative regulators, so it is a key target of study in lymphocyte activation and lymphoma.
| Target | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (gene MALT1; UniProt Q9UDY8, human) |
|---|---|
| Clone | 23M89 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 92.3 kDa |
| Observed MW | 92 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
Samples with a confirmed band (WB): K562 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human MALT1.
Reactivity Notes
The supplier lists reactivity with human. UniProt places mucosa-associated lymphoid tissue lymphoma translocation protein 1 in the cytoplasm and nucleus. Tissue expression noted by UniProt (human): Highly expressed in peripheral blood mononuclear cells. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
