| Field | Specification |
|---|---|
| Target | |
| Alternative names | MARCO; SCARA2; Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human MARCO recombinant protein (Position: M1-R489). Human MARCO shares 66.5% amino acid (aa) sequence identity with mouse MARCO. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes macrophage receptor MARCO in human, mouse and rat samples and is validated for Western blot and ELISA.
MARCO is a class A scavenger receptor expressed on macrophages, notably in the lung, spleen and lymph nodes. It recognizes Gram-positive and Gram-negative bacteria as well as unopsonized particles such as inhaled dust, helping macrophages clear them from tissues. It is studied in innate immunity, lung host defense and particle-induced inflammation.
| Target | Macrophage receptor MARCO (gene MARCO; UniProt Q9UEW3, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human MARCO fragment (Met1–Arg489), expressed in E. coli. Sequence identity with the mouse ortholog: 66.5%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places macrophage receptor MARCO in the cell membrane. Tissue expression noted by UniProt (human): Expressed in alveolar macrophages (at protein level).
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
