| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | MASP1; CRARF; CRARF1; PRSS5; Mannan-binding lectin serine protease 1; EC 3.4.21.-; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; MASP-1; Mannose-binding protein-associated serine protease; Ra-reactive factor serine protease p100; RaRF; Serine protease 5 [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human MASP1 recombinant protein (Position: R169-E580). Human MASP1 shares 84.5% and 83.3% amino acid (aa) sequence identity with mouse and rat MASP1, respectively. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-MASP1 Antibody Picoband® catalog # A02060-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
Cross reactivity: No cross-reactivity with other proteins
Protein: Mannan-binding lectin serine protease 1 | Gene: MBL associated serine protease 1 | Target: MASP1
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: E.coli-derived human MASP1 recombinant protein (Position: R169-E580). Human MASP1 shares 84.5% and 83.3% amino acid (aa) sequence identity with mouse and rat MASP1, respectively. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Observed MW: 79 kDa | Calculated MW: 79 kDa
Status: Active
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