| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human MBD3. Human MBD3 shares 100% amino acid (aa) sequence identity with mouse MBD3. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-MBD3 Antibody Picoband® catalog # A02571-2. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.
Cross reactivity: No cross-reactivity with other proteins
Protein: Methyl-CpG-binding domain protein 3 | Gene: methyl-CpG binding domain protein 3 | Target: MBD3
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MBD3. Human MBD3 shares 100% amino acid (aa) sequence identity with mouse MBD3. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, IF, ICC, ELISA
Observed MW: 33 kDa | Calculated MW: 36 kDa
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.