| Field | Specification |
|---|---|
| Target | |
| Alternative names | Muscleblind-like protein 3; Cys3His CCG1-required protein; Muscleblind-like X-linked protein; Protein HCHCR; MBNL3; CHCR; MBLX39; MBXL |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human MBNL3 recombinant protein (Position: L106-C312). |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody detects muscleblind-like protein 3 (gene MBNL3) in human samples and is validated for Western blot, ICC/IF and ELISA.
MBNL3 (muscleblind-like 3) is an RNA-binding protein of the muscleblind family that regulates alternative splicing of specific pre-mRNAs. It can activate or repress exon inclusion and counteracts the splicing activity of CELF proteins. It is studied in muscle differentiation and regeneration and in relation to myotonic dystrophy.
| Target | Muscleblind-like protein 3 (gene MBNL3; UniProt Q9NUK0, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human) |
|---|---|
| Immunocytochemistry / Immunofluorescence | 5 µg/mL (Human) |
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human MBNL3 fragment (Leu106–Cys312), expressed in E. coli.
Reactivity Notes
The supplier lists reactivity with human. UniProt places muscleblind-like protein 3 in the nucleus and cytoplasm. Tissue expression noted by UniProt (human): Highly expressed in the placenta.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
