| Field | Specification |
|---|---|
| Target | |
| Alternative names | Melanocortin receptor 5; MC5-R; MC-2; MC5R |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human MC5 Receptor |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 27M51 is a rabbit monoclonal antibody that recognizes melanocortin receptor 5 (gene MC5R) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 36.6 kDa, and the supplier reports an observed band at about 45 kDa.
The melanocortin 5 receptor (MC5R) is a G protein-coupled receptor for α-MSH and related melanocortin peptides. It is expressed in many peripheral tissues, particularly exocrine glands, and in rodents it is required for normal sebaceous and other exocrine gland secretion. It is studied in exocrine function, lipid production and immune modulation.
| Target | Melanocortin receptor 5 (gene MC5R; UniProt P33032, human) |
|---|---|
| Clone | 27M51 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 36.6 kDa |
| Observed MW | 45 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Samples with a confirmed band (WB): HeLa cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human MC5 Receptor.
Reactivity Notes
The supplier lists reactivity with human. UniProt places melanocortin receptor 5 in the cell membrane. Tissue expression noted by UniProt (human): Expressed in the brain but not in the melanoma cells. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
