| Field | Specification |
|---|---|
| Alternative Names | DNA replication licensing factor MCM2;3.6.4.12;Minichromosome maintenance protein 2 homolog;Nuclear protein BM28;MCM2;BM28, CCNL1, CDCL1, KIAA0030; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human MCM2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-MCM2 Rabbit Monoclonal Antibody catalog # M00374-2. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
Protein: T-cell surface glycoprotein CD4 | Gene: DNA replication licensing factor MCM2 | Target: MCM2 | Function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. . | Research areas: DNA/RNA,DNA Synthesis,Epigenetics and Nuclear Signaling
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 28M60 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human MCM2 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC, IF, ICC, FC, IP
Observed MW: 125 kDa | Calculated MW: 101896 MW
Cellular localization: Nucleus .
Tissue details: Highly expressed in substantia nigra. .
Status: Active
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