| Field | Specification |
|---|---|
| Target | |
| Alternative names | Protein MGARP; Corneal endothelium-specific protein 1; CESP-1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein; MGARP; C4orf49; CESP1; HUMMR; OSAP |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human C4orf49/MGARP recombinant protein (Position: M1-E155). Human C4orf49/MGARP shares 67.3% amino acid (aa) sequence identity with mouse C4orf49/MGARP. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes protein MGARP in human, mouse and rat samples and is validated for Western blot and ELISA.
MGARP (mitochondria-localized glutamic acid-rich protein) is a mitochondrial protein expressed in steroidogenic tissues, retina and neurons. It regulates the kinesin-driven transport of mitochondria along microtubules, including under hypoxia, and helps maintain mitochondrial abundance and shape. MGARP is studied in mitochondrial trafficking, steroidogenesis and neuronal development.
| Target | Protein MGARP (gene MGARP; UniProt Q8TDB4, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.1–0.25 µg/mL (Human, Mouse, Rat) |
|---|---|
| ELISA | 0.1–0.5 µg/mL |
Immunogen
Recombinant human C4orf49/MGARP fragment (Met1–Glu155), expressed in E. coli. Sequence identity with the mouse ortholog: 67.3%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places protein MGARP in the mitochondrion, mitochondrion outer membrane and mitochondrion inner membrane. Tissue expression noted by UniProt (human): Expressed in the brain, adrenal gland and corneal endothelium (CE).
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
