| Field | Specification |
|---|---|
| Target | |
| Alternative names | Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL; MGLL |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Monoacylglycerol Lipase |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 26M00 is a rabbit monoclonal antibody that recognizes monoglyceride lipase (gene MGLL) in human samples and is validated for Western blot. The predicted molecular weight is 33.3 kDa, and the supplier reports an observed band at about 33 kDa.
Monoacylglycerol lipase (MAGL, MGLL) breaks down monoacylglycerols into glycerol and free fatty acids. It is the main enzyme that inactivates the endocannabinoid 2-arachidonoylglycerol (2-AG), so it shapes endocannabinoid signaling in pain and neuroinflammation, and its supply of free fatty acids makes it a subject of study in lipid metabolism and tumor biology.
| Target | Monoglyceride lipase (gene MGLL; UniProt Q99685, human) |
|---|---|
| Clone | 26M00 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 33.3 kDa |
| Observed MW | 33 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|
Samples with a confirmed band (WB): human heart.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human monoacylglycerol Lipase.
Reactivity Notes
The supplier lists reactivity with human. UniProt places monoglyceride lipase in the cytoplasm and membrane. Tissue expression noted by UniProt (human): Detected in adipose tissue, lung, liver, kidney, brain and heart. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
