Anti-MRP3/ABCC3 Antibody Picoband®

Overview

Anti-MRP3/ABCC3 Antibody Picoband® is an antibody for ABCC3 detection raised in Rabbit (Polyclonal, Rabbit IgG), with reported reactivity: Human. Commonly used in WB, IHC, Flow Cytometry, ELISA workflows.

Key elements and design rationale

• Target: ABCC3 (Fc fragment of IgG receptor Ia); UniProt: O15438
• Antibody format: Rabbit, Polyclonal, Rabbit IgG
• Molecular weight: 200 kDa, calculated 38779 MW
• Applications: WB, IHC, Flow Cytometry, ELISA

Vendor description (summary): Boster Bio Anti-MRP3/ABCC3 Antibody Picoband® catalog # A02429-1.

Biological background

Biological context: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

Expression and localization notes: cellular localization: Cell membrane., tissue context: Monocyte/macrophage specific..

Common research applications

• Western blotting (WB): Compare ABCC3 levels across samples and conditions using appropriate loading and biological controls.
• Immunohistochemistry (IHC): Evaluate spatial distribution of ABCC3 in tissue sections, considering fixation and antigen retrieval effects.
• Flow cytometry: Quantify ABCC3-positive populations in single-cell suspensions with appropriate gating and controls.
• ELISA: Use antibody-based detection formats to assess antigen presence or binding in plate-based assays.

Notes for experimental interpretation

• Account for isoforms, post-translational modifications, and sample-specific processing that can shift apparent molecular weight or epitope accessibility.
• Use positive/negative biological controls where possible (e.g., known-expressing cells/tissues, knockdown/knockout models) and include appropriate secondary-only/isotype controls for imaging workflows.

Additional product notes (from provided fields)

• Background: Canalicular multispecific organic anion transporter 2 is a protein that in humans is encoded by the ABCC3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
• Cross reactivity: No cross-reactivity with other proteins.
• Cellular localization: Cell membrane.
• Tissue details: Monocyte/macrophage specific.
• Research category: Immunoglobulins,Immunology,Innate Immunity

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.