| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | MTHFD2; NMDMC; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase; EC 1.5.1.15; Methenyltetrahydrofolate cyclohydrolase; EC 3.5.4.9] |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human MTHFD2 recombinant protein (Position: R13-N350). Human MTHFD2 shares 92.9% amino acid (aa) sequence identity with mouse MTHFD2. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-MTHFD2 Antibody Picoband® catalog # A06465-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Cross reactivity: No cross-reactivity with other proteins
Protein: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | Gene: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | Target: MTHFD2
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human | Immunogen: E.coli-derived human MTHFD2 recombinant protein (Position: R13-N350). Human MTHFD2 shares 92.9% amino acid (aa) sequence identity with mouse MTHFD2. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, FC, ELISA
Observed MW: 35 kDa | Calculated MW: 38 kDa
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
