| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Lymphatic vessel endothelial hyaluronic acid receptor 1;LYVE-1;Cell surface retention sequence-binding protein 1;CRSBP-1;Extracellular link domain-containing protein 1;Hyaluronic acid receptor;LYVE1;CRSBP1, HAR, XLKD1;UNQ230/PRO263; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human Nck2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-Nck2 Rabbit Monoclonal Antibody catalog # M04036-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Protein: T-cell surface glycoprotein CD3 zeta chain | Gene: Lymphatic vessel endothelial hyaluronic acid receptor 1 | Target: NCK2 | Function: Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. . | Research areas: Cardiovascular,Vasculature
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 28N61 | Isotype: IgG | Reactivity: Human,Mouse,Rat | Immunogen: A synthesized peptide derived from human Nck2 | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC, IF, ICC
Observed MW: 47 kDa | Calculated MW: 35213 MW
Cellular localization: Membrane ; Single-pass type I membrane protein . Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand- dependent internalization and recycling at the cell surface.
Tissue details: Mainly expressed in endothelial cells lining lymphatic vessels. .
Status: Active
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