| Field | Specification |
|---|---|
| Target | |
| Alternative names | Neurturin; NRTN |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | E.coli-derived human Neurturin/NRTN recombinant protein (Position: M1-V197). Human Neurturin/NRTN shares 86.3% amino acid (aa) sequence identity with mouse Neurturin/NRTN. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody targets neurturin (gene NRTN) in human, mouse and rat samples and is validated for Western blot, IHC and ELISA.
Neurturin (NRTN) is a GDNF-family neurotrophic factor. It binds the co-receptor GFRα2 and activates the RET receptor tyrosine kinase, supporting survival of sympathetic, parasympathetic and enteric neurons as well as dopaminergic neurons. It is studied in peripheral nervous system development and in models of Parkinson disease.
| Target | Neurturin (gene NRTN; UniProt Q99748, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Immunogen affinity purified |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4 |
| Reconstitution | 500 µg/mL after adding 0.2 mL distilled water |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25–0.5 µg/mL (Human, Mouse) |
|---|---|
| IHC (paraffin sections) | 2–5 µg/mL (Human, Mouse, Rat) |
| ELISA | 0.1–0.5 µg/mL |
Conditions in the example images (IHC): heat-mediated antigen retrieval in EDTA buffer (pH 8.0).
Immunogen
Recombinant human Neurturin/NRTN fragment (Met1–Val197), expressed in E. coli. Sequence identity with the mouse ortholog: 86.3%.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes neurturin as a secreted protein.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
